Welcome to Southern Spice Restaurant and Grill
Located in the heart of Lake Charles at 3901 Ryan Street, Southern Spice Restaurant and Grill has been delighting guests since 1997 with authentic Southern and Cajun cuisine. Enjoy home-style, made-to-order meals in a warm, family-friendly atmosphere. From hearty classics to flavorful specialties, our full-service dining offers a memorable experience for locals and visitors seeking true Southern comfort.
Delicious Southern and Cajun Flavors
At Southern Spice Restaurant and Grill, every dish is crafted with care and bursting with authentic Southern and Cajun flavors. From hearty gumbo and jambalaya to crispy fried favorites and slow-cooked classics, our home-style meals are made fresh daily using quality ingredients. Whether you’re craving bold spices, comfort food, or family-style portions, every plate delivers a satisfying and memorable taste of Louisiana.
Order Directly from Our Website
Skip the middleman and enjoy the full Southern Spice Restaurant and Grill experience by ordering directly from our website. It’s fast, easy, and ensures your favorite Southern and Cajun dishes arrive just the way you like them. Browse our menu, customize your order, and have delicious, home-style meals ready for pickup or delivery—fresh, flavorful, and made with care every time.
Gallery of Flavor
Explore a visual feast of Southern and Cajun favorites! From hearty gumbo and jambalaya to crispy fried classics and savory sides, our gallery showcases the delicious dishes that make every meal at Southern Spice Restaurant and Grill unforgettable.
A Warm and Welcoming Dining Experience
Step into Southern Spice Restaurant and Grill and enjoy more than just a meal—experience true Southern hospitality in a warm, family-friendly atmosphere. From the moment you arrive, our attentive staff makes every guest feel at home. Savor home-style Southern and Cajun dishes, relax in a comfortable setting, and create memorable moments with family and friends over flavorful, made-to-order meals.
Catering for Every Occasion
Bring the bold flavors of Southern and Cajun cuisine to your next event with catering from Southern Spice Restaurant and Grill. Whether it’s a family gathering, office party, or special celebration, we provide fresh, made-to-order dishes that impress every guest. From savory classics to crowd-pleasing favorites, our full-service catering ensures delicious food, hassle-free setup, and a memorable dining experience for any occasion.
What our guests are saying
This is a classic Southern diner with delicious fried food, wings, seafood, salads, and friendly servers. We were passing through on a trip from South Georgia to Houston, Texas and in a bit of a rush. The waitress served a delicious meal very quickly and we were on our way.
Mark E.
We had a great experience here. The chicken and sausage gumbo was so good (we are so picky when it comes to gumbo, we don't like all those onions in there. There wasn't many and it was delicious!) We also ordered a hamburger and shrimp poboy. We had to take it to go because we were full from the gumbo. Our waitress Kari was amazing, she was very knowledgeable and very sweet. I definitely want to come back for breakfast!
Melissa M
Food was so amazing. Reminded me of a homemade meal I haven’t had in a while. Staff are amazing as well.
Charda O.
Featuring
Catering
Delivery
Takeout
Dine In
Outdoor Seating
Southern Spice Restaurant & Grill Rewards
Join our rewards program, earn points every time you order online, and redeem your points for free food!.
Frequently Asked Questions
What are you known for?
We are known for Fried Okra, Dessert, Chicken and Waffles, Brunch, Onion Rings, Sausage Biscuits, Coffee, Shrimp Poboys, Pancakes, Beignets, Soup, Gumbo, Cheeseburger, Chicken Salad, Crawfish Etouffee, Fish, Cornbread, Waffles, Home Fries, Blt, Mashed Potatoes, Comfort Food, Chili, Breakfast, Chicken Sandwich, Chicken Strips, Crawfish, Sweet Tea, Burgers, Chicken Biscuits, Potato Salad, Seafood, Breakfast Sandwich, Fries, Soul Food, Seafood Gumbo, Cheesecake, Caesar Salad, Fried Shrimp, Baked Potato, Fried Fish, Oatmeal, Salads, Omelet, French Fries, Sausage Biscuit, Sausage, Toast, Meatloaf, Shrimp, Grits, Hot Chocolate, Fried Pickles, Grilled Cheese, Cheese Biscuits, Crab, Wings, Seafood Bisque, Hushpuppies, Eggs, Chicken Wings, Fried Chicken, Grilled Chicken, Chicken Fried Steak, Po Boy, French Toast, Cajun Food, Biscuits, and Chicken Biscuit
Where are you located?
We are located in Lake Charles, LA at 3901 Ryan St
What areas do you serve?
We serve the following areas: Lake Charles, Prien, Hipple, Lockmoor, Westlake, Rose Bluff, Maplewood, Mossville, Chloe, Manchester, Chalkley, Moss Bluff, Ararat, Calcasieu County, Sulphur, Newton, Moss Lake, Carlyss, Goss, Holmwood.
Our location
